The Narcotics Division of the NYPD is responsible for enforcing drug policy and confiscating illegal substances.
- Captain Joey Poole
- Lieutenant Pizzelli
- Detective Brian Cassidy, transferred from Manhattan Special Victims Unit
- Detective Odafin Tutuola, transferred to Manhattan Special Victims Unit
- Detective Joey Bosco
- Detective Brad Kendall, deceased
- Detective Miguel Sandoval
- Lieutenant Toni Howard, former supervisor
- Sergeant Frank Foster, arrested
- Detective Odafin Tutuola, transferred to Manhattan Narcotics.
- Detective Luis Montero, retired on disability after taking a bullet meant for Fin.
- Detective Robert Goren, transferred to Manhattan Major Case Squad.
- Detective Mallory